Myeloma Cast Nephropathy

Myeloma Cast Nephropathy Doctors in Arizona

Myeloma cast nephropathy, also known as light chain cast nephropathy, is a severe kidney complication of multiple myeloma, a type of cancer that affects plasma cells. It occurs when large amounts of abnormal proteins, called light chains, are produced and build up in the kidneys, causing significant damage. Our specialists provide compassionate and timely care to diagnose and manage this complex condition.

What is Myeloma Kidney Damage?

Excess light chains can form dense blockages, or “casts,” that obstruct the kidney’s filtering tubules and may cause kidney failure. This type of damage is a primary cause of myeloma kidney disease. Symptoms may include a sudden decrease in urine output, swelling in the legs, fatigue, or nausea, although signs may not be noticeable in the early stages.

Comprehensive Treatment for Myeloma Kidney Disease in Arizona

Treating myeloma cast nephropathy requires a coordinated approach. The primary goal is to treat the underlying multiple myeloma with chemotherapy to reduce the production of the harmful light chains. Simultaneously, our nephrology team provides supportive care, which may include short-term dialysis, to help the kidneys recover. This collaborative approach is essential for the best possible outcome.

Board-Certified Nephrology Care in Arizona

If you’re living with multiple myeloma and notice new leg or ankle swelling, rising fatigue, reduced or foamy urine, or flank discomfort, don’t wait—request a kidney assessment right away. Southwest Kidney Institute’s myeloma-focused nephrologists diagnose and treat light-chain cast nephropathy and other myeloma-related renal problems. We coordinate closely with your oncology team to start targeted therapy, protect kidney function, and keep your overall treatment plan on track.